SEKER HASTALIGI-DIYABET (DIABET)-Prof Dr Metin Ozata

DIYABET İLE ILGILI BILIMSEL CALISMALARDAN OZETLER

 

1. KAN FERRITIN YUKSEKLIGI DIABET YAPIYOR

JCEM Aralik 2008 de yayinlanan bir calismada kan ferritin duzeyi yani demir duzeyi arttıkce seker hastaligi riski artmakta oldugu saptandı.

Liang Sun, Oscar H. Franco, Frank B. Hu, Lu Cai, Zhijie Yu, Huaixing Li, Xingwang Ye, Qibin Qi, Jing Wang, An Pan, Yong Liu, and Xu Lin Ferritin Concentrations, Metabolic Syndrome, and Type 2 Diabetes in Middle-Aged and Elderly Chinese
J Clin Endocrinol Metab 2008 93: 4690-4696 , doi:10.1210/jc.2008-1159 [Abstract] [Full Text] [PDF] [Supplemental Data]  
In middle-aged and elderly Chinese, elevated plasma ferritin is independently associated with higher risk of type 2 diabetes and metabolic syndrome, suggesting the crucial role of iron overload in developing countries.

 

2. UZUN SURE DUSUK DOZ ASPIRIN ALAN KADINLARDA ASPIRIN ALMAK DIYABET GELISIMINI ENGELLEMIYOR

 

 A Randomized Trial of Low-Dose Aspirin in the Prevention of Clinical Type 2 Diabetes in Women Aruna D. Pradhan, Nancy R. Cook, JoAnn E. Manson, Paul M. Ridker, and Julie E. Buring
Diabetes Care 2009 32: 3-8.

3. EGZERSIZ SEKER HASTALIGI GELISIMINI ENGELLIYOR

Physical Activity May Facilitate Diabetes Prevention in Adolescents Amy S. Thomas, Lori F. Greene, Jamy D. Ard, Robert A. Oster, Betty E. Darnell, and Barbara A. Gower
Diabetes Care 2009 32: 9-13.

 

4. TANSIYON YUKSEKLIGI VE KAN SEKERI YUKSEKLIGI KORONER ARTER HASTALIGINA KATKIDA BULUNUYOR

  Blood Pressure and Fasting Plasma Glucose Rather Than Metabolic Syndrome Predict Coronary Artery Calcium Progression: The Rancho Bernardo Study Caroline K. Kramer, Denise von Mühlen, Jorge L. Gross, Gail A. Laughlin, and Elizabeth Barrett-Connor
Diabetes Care 2009 32: 141-146

 

5.  DIYABET VE TRIGLISERID YUKSEKLIGI DEMANS-ALZHEIMER  RISKINI ARTIRIYOR

 Metabolic Syndrome and Risk for Incident Alzheimer's Disease or Vascular Dementia: The Three-City Study Christelle Raffaitin, Henri Gin, Jean-Philippe Empana, Catherine Helmer, Claudine Berr, Christophe Tzourio, Florence Portet, Jean-François Dartigues, Annick Alpérovitch, and Pascale Barberger-Gateau
Diabetes Care 2009 32: 169-174

 

6. SEKER KONTROLUNUN IYI OLMASI VE HBA1c nin 6.5 altında olması Diyabet komplikasyonlarından koruyor

 

Tip 1 diyabetli hastalrda yapilan DCCT calısmasında 6.5 yıllık bir takip sonrası iyi kan sekeri kontrolu olan hastalarda diyabet goz hastalıgı, nefropati (bobrek hasarı) ve noropati % 60 oranında azaliyor. 

UKPDS isimli calismada ise tip 2 diyabetli hastalarda 10 yıl yapılan gozlem ile kan sekeri iyi kontrolde olan hastalarda komplikasyonlar % 25 daha az goruldu. 

Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials: A position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association

Jay S. Skyler, Richard Bergenstal, Robert O. Bonow, John Buse, Prakash Deedwania, Edwin A.M. Gale, Barbara V. Howard, M. Sue Kirkman, Mikhail Kosiborod, Peter Reaven, and Robert S. Sherwin
Diabetes Care 2009 32: 187-19

 

 7. SEKER HASTALIGI TEDAVISINDE METFORMIN VE YASAM DEGISIKLIGI ILE YETERLI KONTROL SAGLANAMAZ ISE DIGER ILACLARI ILAVE ETMEK GEREKIR

metformin ile yetrli cevap alınamaz ise 3 ay icine ikinci ilaca baslamak gerekir. eger bununla da kontrol olmaz ise insulin tedavisine gecilebilir

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes David M. Nathan, John B. Buse, Mayer B. Davidson, Ele Ferrannini, Rury R. Holman, Robert Sherwin, and Bernard Zinman
Diabetes Care 2009 32: 193-20

 

8. YATMADAN ONCE ALINAN 2.5 mg TERBUTALIN TIP 1 DIYABETIKLERDE GECE HIPOGLISEMILERINI ONLEMEDE FAYDALI ANCAK SABAH KAN SEKERI YUKSELIYOR

 Terbutaline and the Prevention of Nocturnal Hypoglycemia in Type 1 Diabetes Benjamin A. Cooperberg, Suzanne M. Breckenridge, Ana Maria Arbelaez, and Philip E. Cryer
Diabetes Care 2008 31: 2271-2272

 

9. VITAMIN K ILAVE ALINMASININ INSULIN DIRENCINE YASLILARDA FAYDALI OLDUGU IDDIA EDILIYOR

Effect of Vitamin K Supplementation on Insulin Resistance in Older Men and Women Makiko Yoshida, Paul F. Jacques, James B. Meigs, Edward Saltzman, M. Kyla Shea, Caren Gundberg, Bess Dawson-Hughes, Gerard Dallal, and Sarah L. Booth
Diabetes Care 2008 31: 2092-2096

 

10. YUKSEK ENERJILI-KALORILI GIDA YIYENLERDE TIP 2 DIYABET DAHA CABUK ORTAYA CIKIYOR

 Dietary Energy Density Predicts the Risk of Incident Type 2 Diabetes: The European Prospective Investigation of Cancer (EPIC)-Norfolk Study Jing Wang, Robert Luben, Kay-Tee Khaw, Sheila Bingham, Nicholas J. Wareham, and Nita G. Forouhi
Diabetes Care 2008 31: 2120-2125

 

11. PRE-DIYABET YANI GIZLI SEKER DE SEKER HASTALIGI GIBI TEDAVI EDILMELI, KILO VERMELI VE EGZERSIZ YAPILMALI

 

Influence of Race, Ethnicity, and Culture on Childhood Obesity: Implications for Prevention and Treatment: A consensus statement of Shaping America's Health and the Obesity Society

Sonia Caprio, Stephen R. Daniels, Adam Drewnowski, Francine R. Kaufman, Lawrence A. Palinkas, Arlan L. Rosenbloom, and Jeffrey B. Schwimmer
Diabetes Care 2008 31: 2211-2221

 12. YENI BASLAYAN VE KAN SEKERI COK YUKSEK OLAN SEKER HASTALARINDA INSULIN TEDAVISI BASARILI VE FAYDALI OLUYOR

 Beneficial Effects of Insulin on Glycemic Control and β-Cell Function in Newly Diagnosed Type 2 Diabetes With Severe Hyperglycemia After Short-Term Intensive Insulin Therapy Harn-Shen Chen, Tzu-En Wu, Tjin-Shing Jap, Li-Chuan Hsiao, Shen-Hung Lee, and Hong-Da Lin
Diabetes Care 2008 31: 1927-1932

 

13. GEBELIK SON AYLARINDA HbA1c DUZEYI DEMIR EKSIKLIGI NEDENIYLE YUKSEK CIKMAKTADIR.

 

A1C but Not Serum Glycated Albumin Is Elevated in Late Pregnancy Owing to Iron Deficiency Kunihiko Hashimoto, Sanai Noguchi, Yasuhiko Morimoto, Shinichi Hamada, Kenshi Wasada, Shiro Imai, Yuji Murata, Soji Kasayama, and Masafumi Koga
Diabetes Care 2008 31: 1945-1948

14. GIZLI SEKERI OLAN KISILERDE 2 GUN YAPILAN EGITIM VE 3 AYDA BIR BU EGITIMIN TEKRARLANMASI GIZLI SEKERDEN SEKER HASTALIGINA GECISI AZALTIYOR

Reduced Progression to Type 2 Diabetes From Impaired Glucose Tolerance After a 2-Day In-Hospital Diabetes Educational Program: The Joetsu Diabetes Prevention Trial Tetsuya Kawahara, Keiichi Takahashi, Tetsuya Inazu, Tadashi Arao, Chie Kawahara, Takahiro Tabata, Hiroyuki Moriyama, Yosuke Okada, Emiko Morita, and Yoshiya Tanaka
Diabetes Care 2008 31: 1949-1954

 

15. YENI TANI KONAN SEKER HASTALARINDA KILO VERME KAN SEKERI VE TANSIYONU DUZELTIYOR.,

 Weight Change in Diabetes and Glycemic and Blood Pressure Control Adrianne C. Feldstein, Gregory A. Nichols, David H. Smith, Victor J. Stevens, Keith Bachman, A. Gabriela Rosales, and Nancy Perrin
Diabetes Care 2008 31: 1960-1965

 

16. GENC YASTA TIP 2 DIYABET BASLAYANLARDA GOZ HASARI YANI RETINIOPATI DAHA ERKEN ORTAYA CIKABILIYOR.

 Timing Is Everything: Age of Onset Influences Long-Term Retinopathy Risk in Type 2 Diabetes, Independent of Traditional Risk Factors Jencia Wong, Lynda Molyneaux, Maria Constantino, Stephen M. Twigg, and Dennis K. Yue
Diabetes Care 2008 31: 1985-1990

 

17. DIYABETI OLMAYAN SAGLIKLI KISILERDE YAS ARTTIKCA HBA1c  YUKSELIYOR

 

 Effect of Aging on A1C Levels in Individuals Without Diabetes: Evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001–2004 Lydie N. Pani, Leslie Korenda, James B. Meigs, Cynthia Driver, Shadi Chamany, Caroline S. Fox, Lisa Sullivan, Ralph B. D’Agostino, and David M. Nathan
Diabetes Care 2008 31: 1991-1996.

 

18. DIYABETLI HASTALARDA PARKINSON HASTALIGI RISKI ARTMIYOR

 Prospective Cohort Study of Type 2 Diabetes and the Risk of Parkinson's Disease Jane A. Driver, Ashley Smith, Julie E. Buring, J. Michael Gaziano, Tobias Kurth, and Giancarlo Logroscino
Diabetes Care 2008 31: 2003-2005.

 

19. ERKEK TIP 1 ve TIP 2 DIYABETLI   GENC HASTALARDA TESTOSTERON DUZEYI DAHA DUSUK ve FSH ve LH HORMONLARI DUSUK YANI HIPOGONADOTROPIK HIPOGONADIZM VARDIR

 

  Testosterone Concentration in Young Patients With Diabetes Anil Chandel, Sandeep Dhindsa, Shehzad Topiwala, Ajay Chaudhuri, and Paresh Dandona
Diabetes Care 2008 31: 2013-2017

 

20. GEBELIKTE DIYABET YANI  GEBELIKTE SEKER  HASTALIGI OLANLARDA DOGUM SONRASI SEKER HASTALIGI RISKI FAZLA

  Glucose Intolerance in Pregnancy and Future Risk of Pre-Diabetes or Diabetes Ravi Retnakaran, Ying Qi, Mathew Sermer, Philip W Connelly, Anthony J.G. Hanley, and Bernard Zinman
Diabetes Care 2008 31: 2026-2031

 

21. KAN YAGI TRIGLISERID DUZEYI YUKSEK OLANLARDA SEKER HASTALIGI GELISME RISKI FAZLA VE BU DURUM 5 YILDA BIR OLCULEN KAN TRIGLISERID DUZEYI ILE TAHMIN EDILEBILECEGI IDDIA EDILMEKTE

 

 Changes in Triglyceride Levels Over Time and Risk of Type 2 Diabetes in Young Men Amir Tirosh, Iris Shai, Rafael Bitzur, Ilan Kochba, Dorit Tekes-Manova, Eran Israeli, Tzippora Shochat, and Assaf Rudich
Diabetes Care 2008 31: 2032-2037

22. SEKER HASTALIGI ORTAYA CIKACAGINI ORTAYA KOYAN EN ONEMLI BULGU YAGLILIK YANI SISMANLIK VE KAN SEKERIDIR.

Predicting Diabetes: Clinical, Biological, and Genetic Approaches: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Beverley Balkau, Céline Lange, Leopold Fezeu, Jean Tichet, Blandine de Lauzon-Guillain, Sebastien Czernichow, Frederic Fumeron, Philippe Froguel, Martine Vaxillaire, Stephane Cauchi, Pierre Ducimetière, and Eveline Eschwège
Diabetes Care 2008 31: 2056-2061

 

23. TIP 1 DIYABETLI KIZLARDA 20 YASLARINDA KEMIK ERIMESI SIKLIGI FAZLA VE YAS ILERLEDIKCE DEVAM EDIYOR

 Young Women With Type 1 Diabetes Have Lower Bone Mineral Density That Persists Over Time Lucy D. Mastrandrea, Jean Wactawski-Wende, Richard P. Donahue, Kathleen M. Hovey, Angela Clark, and Teresa Quattrin
Diabetes Care 2008 31: 1729-1735

 

24. TIP 2 DIYABETLI HASTALARDA OLUM ORANI SON YILLARDA AZALIYOR VE BUNUN NEDENI KAN SEKERI , TANSIYON ve KAN YAGLARININ IYI KONTROLUDUR

Explaining the Decline in Early Mortality in Men and Women With Type 2 Diabetes: A population-based cohort study Judith Charlton, Radoslav Latinovic, and Martin C. Gulliford
Diabetes Care 2008 31: 1761-1766

 

25. TOPLUMDA HER 3 SEKER HASTASINDAN BIRISI KENDINDE DIYABET YANI SEKER HASTALIGI OLDUGUNDAN HABERSIZ

 Obesity and Undiagnosed Diabetes in the U.S. Christina C. Wee, Mary Beth Hamel, Annong Huang, Roger B. Davis, Murray A. Mittleman, and Ellen P. McCarthy
Diabetes Care 2008 31: 1813-1815

 

26. GEBELIK DIYABETI YANI GEBELIKTE SEKERI YUKSEK OLAN KADINLARDA DAHA SONRAKI GEBELIKTE DIYABET CIKMA OLASILIGI YUKSEK VE BU DURUM DOGUMDAN 2 AY SONRA OLCULEN KAN SEKERI ILE TAHMIN EDILEBILIR

Subsequent Pregnancy After Gestational Diabetes Mellitus: Frequency and risk factors for recurrence in Korean women Soo Heon Kwak, Hae Sung Kim, Sung Hee Choi, Soo Lim, Young Min Cho, Kyong Soo Park, Hak C. Jang, Moon Young Kim, Nam H. Cho, and Boyd E. Metzger
Diabetes Care 2008 31: 1867-1871

27. KATARAKT, GOZ TANSIYONU VE DIGER GOZ HASTALIKLARI SEKER HASTALARINDA DAHA SIK GORULUYOR VE BU NEDENLE SEKER HASTALARI MUTLAKA YILDA EN AZ  BIR DEFA GOZ MUAYENESI OLMALI

 Ocular Associations of Diabetes Other Than Diabetic Retinopathy

V. Swetha E. Jeganathan, Jie Jin Wang, and Tien Yin Wong

Diabetes Care 2008 31: 1905-1912

 

 

 

28. KAN URIK ASIT DUZEYI YUKSEK OLANLARDA VE HEPATIT C VIRUSU TASIYANLARDA DIYABET-SEKER HASTALIGI GELISME RISKI FAZLA

 

 

High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes: Response to Dehghan et al.

Chia-Yen Dai, Wan-Long Chuang, Chi-Kong Ho, Tsan-Teng Ou, Jee-Fu Huang, Ming-Yen Hsieh, and Ming-Lung Yu
Diabetes Care 2008 31: e67

 

 

 

28. HbA1c olcumu  TAHMINI ORTALAMA KAN SEKERI DEGERINI VERIR

 

 

 

Asagıdaki Tabloda Hangi Hba1c degerinin hangi tahmini  kan sekerine karsilik geldigi gorulmekte.

HbA1C (%)   Kan Sekeri (mg/dl)
   5             97 (76–120)
   6             126 (100–152)
   7             154 (123–185)
   8            183 (147–217)
   9             212 (170–249)
  10            240 (193–282)
  11             269 (217–314)
  12             298 (240–347) 

 

Translating the A1C Assay Into Estimated Average Glucose Values David M. Nathan, Judith Kuenen, Rikke Borg, Hui Zheng, David Schoenfeld, Robert J. Heine for the A1c-Derived Average Glucose (ADAG) Study Group
Diabetes Care 2008 31: 1473-1478

 

 

29. FENOFIBRAT VE KOENZIM Q 10 KULLANIMI KALP DIASTOLIK FONKSIYONUNA FAYDALI DEGIL ANCAK TANSIYONDA DUSME YAPIYOR

 

Hemodynamic Effects of Fenofibrate and Coenzyme Q₁₀ in Type 2 Diabetic Subjects With Left Ventricular Diastolic Dysfunction Gerard T. Chew, Gerald F. Watts, Timothy M.E. Davis, Bronwyn G.A. Stuckey, Lawrence J. Beilin, Peter L. Thompson, Valerie Burke, and Philip J. Currie
Diabetes Care 2008 31: 1502-1509

 

30 DIYABET HASTALARINDA PNOMONI YANI ZATURRE RISKI FAZLA VE PNOMOKOK ASISI YAPILMALI

 Diabetes, Glycemic Control, and Risk of Hospitalization With Pneumonia: A population-based case-control study Jette B. Kornum, Reimar W. Thomsen, Anders Riis, Hans-Henrik Lervang, Henrik C. Schønheyder, and Henrik T. Sørensen
Diabetes Care 2008 31: 1541-1545.

 

31. SEKER YUKLEME TESTINDE (OGTT) 1. SAAT KAN SEKERI 155 mg/dl Ve UZERINDE CIKARSA BU KISILERDE  ILERIDE SEKER HASTALIGI-DIYABET CIKMA OLASILIGI YUKSEKTIR VE ONLEM ALMALIDIRLAR

 

One-Hour Plasma Glucose Concentration and the Metabolic Syndrome Identify Subjects at High Risk for Future Type 2 Diabetes Muhammad A. Abdul-Ghani, Tamam Abdul-Ghani, Nibal Ali, and Ralph A. DeFronzo
Diabetes Care 2008 31: 1650-1655

 

32. SEKER HASTALARI HER GUN AYAK BAKIMI YAPMALI VE AYAKLARINI YIKAMALI VE NASIR VARSA TEDAVI ETTIRMELI

 

Comprehensive Foot Examination and Risk Assessment: A report of the Task Force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists

Andrew J.M. Boulton, David G. Armstrong, Stephen F. Albert, Robert G. Frykberg, Richard Hellman, M. Sue Kirkman, Lawrence A. Lavery, Joseph W. LeMaster, Joseph L. Mills, Sr., Michael J. Mueller, Peter Sheehan, and Dane K. Wukich
Diabetes Care 2008 31: 1679-1685